GLUTAMINE POWDER BY ECLIPSE SPORT SUPPLEMENTS
The Conditionally Essential Amino Acid
Glutamine has an important structural role, comprising 5-10% of amino acid residues in various proteins. Glutamine is a major vehicle for the transfer of nitrogen between tissues. Maximum growth and proliferation of most cell types occur with adequate glutamine stores. Dependence on glutamine for cellular growth and function has been clearly demonstrated for intestinal mucosal cells and cells of the immune system.
Glutamine plays a key part with the branched chain amino acids (BCAA) in muscle energy metabolism and the over training syndrome of athletes. Approximately, 55% of glutamine taken up is oxidized via alpha-ketogluterate and the Krebs cycle to form CO2 and a further 20% is incorporated into citrate, lactate, organic acids, and glucose. Most glutamine is partly metabolized to form alanine and lactate.
During fever, surgery, and trauma muscle free glutamine concentrations fall. Adequate circulating glutamine is needed for mucosal healing and muscle protein synthesis; therefore glutamine may be considered “conditionally essential.” Studies suggest that providing increased oral protein intake can replete muscle glutamine concentrations.